Completed Projects | BBMRI-ERIC: Making New Treatments Possible
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Completed Projects

BioMedBridges

Building data bridges and services between biological and medical infrastructures in Europe

Topic: FP7 INFRA-2011-2.3.2
Type of Action: CP-CSA Infra
Duration: 36 months
Start Date: 1 January 2012
BBMRI-ERIC full partner: as of 1 October 2014
Grant Agreement Nr: 284209
Web: http://www.biomedbridges.eu/
Coordinator: Janet Thornton
Total requested Grant by Consortium: € 10,494,998.69
Total requested Grant by BBMRI-ERIC: € 8,400.00
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: Connecting BMS RIs

 

Lead by European Molecular Biology Laboratory: BioMedBridges (Building data bridges and services between biological and medical infrastructures in Europe) will form a cluster of the emerging biomedical sciences research infrastructures (BMS RIs) and construct the data and service bridges needed to connect them.

The BMS RIs are on the ESFRI (European Strategy Forum on Research Infrastructure) roadmap. The missions of the BMS RIs stretch from structural biology of specific biomolecules to clinical trials involving thousands of human patients. Most serve a specific part of the vast biological and medical research community, estimated to be at least two million scientists in Europe across more than 1,000 institutions from more than 36 ESFRI Member States and Associated Countries. Each of them brings together its own large community of users to build a coordinated infrastructure.

This process has already had a major impact on coordination of national infrastructures within each member state. Essentially all BMS RIs are distributed infrastructures, with nodes in many European member states.

List of Participants

European Molecular Biology Laboratory/ELIXIR, University of Oxford, Karolinska Institutet, Science and Technology Facilites Council, Heinrich Heine Universität Düsseldorf, Leibnitz-Institut für Molekulare Pharmakologie, Technische Universität München, Stazione Zoologica Anton Dohm, Erasmus University Medical Center Rotterdam, Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V, Helmholtz Zentrum München, Medizinische Universität Graz, Stichting VU-VUmc, Institut national de la santé et de la recherche médicale, University of Copenhagen, University of Helsinki/Institute for Molecular Medicine Finland, European Grid Infrastructure, CSC-IT Center for Science Ltd., University Medical Center Groningen, Consorzio Interuniversitario di Risonanze Magnetiche di Metalloproteine, Delivery of Advanced Network Technology to Europe


 

CY-Biobank

Biobanking and the
Cyprus Human Genome Project

Topic: H2020-WIDESPREAD-2014-1
Type of Action: FPA-SGA
Duration: 12 months
Start Date: 1 September 2015
Grant Agreement Nr: 664561
Web:  http://www.ucy.ac.cy/cybiobank/en/
Coordinator:  Constantinos Deltas
Total requested Grant by Consortium: €460,637.50
Total requested Grant by BBMRI-ERIC:  €64,475.00
Linked Third Parties/BBMRI-ERIC Framework Agreement:
none
Benefit/tasks for BBMRI-ERIC: Work Package 5: Standards, ELSI Compliance and Data Management; Task 5.1: Standards/Procedures Adoption & Quality Processes; Task 5.2: ELSI Compliance; Task 5.3: Data Management Plan (raw data availability and Gold access policy); Task 5.1/Deliverable 5.1, Task 5.2/Deliverable 5.2, Task 5.3/Deliverable 5.3

 

Lead by University of Cyprus: The upgrading of MMRC into a CoE and its close partnership with the named Advanced Partners is a safe and sound strategy that will assist Cyprus over the next decade to enter large European networks and participate at ongoing and future epidemiological studies with mutual benefit to the Cypriot and the European patients.

List of Participants: University of Cyprus, Medical University of Graz/BBMRI.at, BBMRI-ERIC, RTD Talos Limited


 

EMTRAIN, EU project, BBMRI-ERIC

EMTRAIN

European Medicines Research
TRAIning Network

Topic: FP7/2007-2013
Type of Action: IMI
Duration: 84 months
Start Date: 1 October 2009
BBMRI-ERIC full partner: as of 1 October 2015
Grant Agreement Nr: 115015
Web: http://www.emtrain.eu/
Coordinator: Mike Hardman
Total requested Grant by Consortium: €4,000,000.00
Total requested Grant by BBMRI-ERIC: €9,754.45
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: Education & training platform, IMI (Innovative Medicines Initiative)

 

Lead by Astra Zeneca

EMTRAIN will establish a pan-European platform for education and training covering the whole lifecycle of medicines from basic research through clinical development to pharmaco-vigilance. The public consortium consists of the six pan-European biomedical research infrastructures from the ESFRI roadmap, that cover a broad spectrum of competencies from molecules to humans, with a pan-European dimension. The EFPIA consortium has considerable experience in training and education, management, pan-European geographical outreach, and an extensive external network of contacts. The participants, together with the coordinators of IMI&T topics will participate in the Strategic Co-ordination Board to ensure coordination between the IMI&T topics whereas the Steering Committee will supervise the management of the project. E&T (Education and Training) topics representatives will be invited to participate in work packages activities. Based on extensive mapping of existing resources and on a gap and overlap analysis (Work Package 3) the consortium will develop and implement a strategy for harmonisation and accreditation (Work Package 4) of Master level Work Package 5) and PhD programmes (Work Package 6) as well as continuous education programmes (Work Package 7). It will develop innovative concepts and methods in conjunction with the other topics (Work Package 8) that will support the content for the IMI education programmes. National implementation will be facilitated through contacts with university authorities, ministries of higher education, and through national liaison offices. After implementation in a core group of institutions, extension is planned both within countries represented and in additional countries (Work Package 4), with the support of a dissemination and communication activity (Work Package 9) The harmonisation and the modular nature of these programmes will allow trans-disciplinary curricula as well as trans-border mobility, and PhD programmes will be designed to foster industry/academia mobility and collaboration.

List of Participants

AstraZeneca, Genzyme, Novartis, Bayer, Pfizer, Roche, GSK, UCB, Novo Nordisk, Sanofi, Boehringer Ingelheim, Janssen Pharmaceuticals, Orion, Almirall, Ludnbeck, Esteve, Medizinische Universität Wien (ECRINpartner), Karolinska Insititute (EATRIS partner), KUK (ECRIN partner), UniMan (BBMRI partner) ECRIN-ERIC, BBMRI-ERIC, EMBL-EBI (ELIXIR partner), HZI (EATRIS partner), GIE-CERBM (Infrafrontier partner), UOX (Instruct partner), MRC-HU (ECRIN partner) Institute of Human Virology, Nigeria


 

EGI-Engage

Engaging the EGI Community towards an Open Science Commons

Topic: H2020 EGI-EINFRA-1-6
Type of Action: RIA
Duration: 30 months
Start Date: 1 May 2015
Grant Agreement Nr:  654142
Web:  https://www.egi.eu/about/egi-engage/
Coordinator:  Tiziana Ferrari
Total requested Grant by Consortium: €8,000,000.00
Total requested Grant by BBMRI-ERIC: €128,550.00 (includes funds for linked third parties)
Linked Third Parties/BBMRI-ERIC Framework Agreement:
BBMRI.cz/Masaryc University, BBMRI.se/KI, BBMRI.nl/LUMC
Benefit/tasks for BBMRI-ERIC: Work Package 1: Technology exchange, outreach, training and support with the following deliverables; Task 1.1: Support and outreach to the user community Task 1.3: Coordination.

Lead by Stichting European Grid Initiative: High-throughput technologies are more accessible to research-biobanking and the number of biobanks providing services that require large storage capability and parallel data analysis is increasing dramatically. Moreover, data from multiple biobanks must now be pooled to reach statistical power to elucidate meaningful associations, while complying with legal and regulatory issues. This BBMRI-ERIC EGI (European Clinical Research Infrastructures Network) Competence Centre thus focuses on helping BBMRI-ERIC to bridge this gap with the implementation of big data storage in combination with data analysis and data federation using EGI federated cloud infrastructure.

List of Participants: Stichting European Grid Initiative, Oesterreichische Akademie der Wissenschaften, Vlaams Instituut voor de Zee VZW, Institute of Information and Communication Technologies, – Bulgarian Academy of Sciences, Swiss National Grid Association, CESNET, Zajmove Sdruzeni Pravnickych OSOB, Fraunhofer-Gesellschaft zur Foerderung der Angew Andten Forschung E.V, Gesellschaft fur Wissenschaftliche Datenverarbeitung MBH Gottingen, Agnecia Estatal Consejo Superior de Investigaciones Cientificas, CSC-Tieteen Tietotekniikan Keskus Oy, Centre Nationale de la Recherche Scientifique, Institut National de la Recherche Agronomique, The Greek Research and Technology Network S.A., Sveuciliste u Zagrebu Sveučilišni Računski Centar, Magyar Tudomanyos Akademia Szamitastechnikai es Automatizalasi  Kutatointezet, Istituto Nazionale di Fisica Nucleare, Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine, Provincia Lombardo Veneta Ordine Ospedaliero di San Giovanni di Dio – Fatebenefratelli, Consiglio Nazionale delle Ricerche, Engineering – Ingegneria Informatica SpA, SURFsara B.V, Akademia Górniczo-Hutnicza im. Stanisława Staszica – Academic Computer Centre CYFRONET AGH, Laboratorio de Instrumentacao e Fisica Experimental de Particulas, ICETA – Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Institut za Fiziku, Beograd, Uppsala Universitet – Swedish National Infrastructure for Computing, Ustav Informatiky, Slovenska Akademia Vied, Turkiye Bilimsel ve Teknolojik Arastirma Kurumu, Science and Technology Facilities Council, Biobanking and BioMolecular resources Research Infrastructure – European Research Infrastructure Consortium, European Molecular Biology Laboratory, European Organisation for Nuclear Research, EISCAT Scientific Association, Food and Agriculture Organisation of the United Nations, Agro-Know I.K.E, Maat France SARL, The Trustees of Indiana University, Academia Sinica, Advance Science and Technology Institute, Institut Teknologi Bandung BHMN, Korea Institute of Science and Technology Information, Universiti Putra Malaysia, National Science & Technology Development Agency


 

BBMRI-LPC

Biobanking and Biomolecular Resources Research Infrastructure – Large Prospective Cohorts

Topic: INFRA-2012-1.1.9
Type of Action: CP&CSA
Duration: 57 months
Start Date: 1 February 2013 – 31 October 2017
BBMRI-ERIC full partner: as of 1 April 2014
Web: https://cordis.europa.eu/project/rcn/108236_de.html
Coordinator: Markus Perola
Co-Coordinator: Gertjan van Ommen
Total requested Grant by Consortium: €8,000,000.00
Total requested Grant by BBMRI-ERIC: €14,552.00
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: BBMRI-LPC Forum, BBMRI-ERIC

 

Abstract:

Lead by UH-FIMM.
BBMRI-LPC unites the large study sets of the European Biobanking and Biomolecular resources Research Infrastructure (BBMRI) and the International Agency for Research on Cancer (IARC), thus achieving a worldwide unique scale of integration.

Specifically, we aim to:
1.      Evaluate/improve the harmonisation of individual data on health, lifestyle and other exposures;

2.      Develop/implement harmonised definitions of diseases;

3.      Improve biobanking and research technologies and develop innovative solutions facilitating high-quality, fair transnational access to samples and data;

4.      Provide free transnational access by users, through study proposals selected by an open, pan-European call;

5.      In the framework of these studies, generate and provide access to whole genome sequences, transcriptome, proteome, metabolome and methylome data;

6.      Build new public-private partnerships involving large-scale prospective cohorts, and strengthening existing ones, allowing transparent industrial access to academic expertise;

7.      Build a network transferring the expertise of established European large-scale biobanks to new biobank initiatives under development in other countries (BBMRI-LPC Forum).

 

List of Participants:

Helsingin Yliopisto (UH-FIMM); Academisch Ziekenhuis Leiden Leid Universitair Medisch Centrum (LUMC); Centre International de Recherche Sur le Cancer (IARC-WHO); Imperial College of Science, Technology and Medicine (ICL); Medizinische Universitat Graz MEDUNI Graz (MUG); Karolinska Institutet(KI); Genome Research Limited (WTSI); Academisch Ziekenhuis Groningen (UMCG); Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit un Umwelt GmBh (HMGU); Norges Teknisk Naturvitenskapelige Universitet (NTNU); Tartu Ulikool (UTARTU); Uppsala Universitet (UU); Centre Nacional D’Anàlisi Genòmica Fundacio Centre de Regulacio Genomica (CNAG-CRG); Cambridge Protein Arrays LTD (CPA); Pecsi Tudomanyegyetem University of PECS (UP); The Research Institute of the Mc Gill University Health Centre (RI MUHC); Legal Pathways BV (Legal Pathways); Islensk Erfdagreining EHF (DECODE); Terveyden Ja Hyvinvoinnin Laitos (THL); International Prevention ResearchInstitut IPRI Management (IPRI); Latvijas Biomedicinas Petijumu un Studiju Centrs (LBMC); Sveuciliste U Splitu University of SPLIT (CCGH); Wroclawskie Centrum Badan EIT + Sp. z o.o. (EIT+); Klinikum Rechts der Isar der Technischen Universitat Munchen (TUM-MED); Institut national de la Sante et de lat Recherche Medicale (INSERM); MedLawconsult (Medlaw); Universiteit Maastricht (MU); Nasjonalt Folkehelseinstitutt (NIPH); Statens Serum Institut (SSI), University of Bristol (UBRIS), BBMRI-ERIC, Universita Degli Stufi di Milano Bicocca (UNIMIB)


 

 

B3Africa logo

B3AFRICA

Bridging Biobanking and Biomedical Research across Europe and Africa

Topic: INFRASUPP-6-2014
Type of Action: CSA
Duration: 36 months
Start Date: 1 July 2015
Grant Agreement Nr: 654404
Web: http://www.b3africa.org/
Coordinator: Erik Bongcam-Rudloff
Total requested Grant by Consortium: €201,250.00
Total requested Grant by BBMRI-ERIC: €70,000.00
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: contacts to Africa, ELSI activities will be informative for the work of the Common Service ELSI

Lead by Sverige Lantbruksuniversitet

B3Africa (Bridging Biobanking and Biomedical Research across Europe and Africa) will dramatically improve and facilitate the development of better predictive, preventive and personalised healthcare worldwide. The rapidly evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information to advance biomedical research. B3Africa aims to implement a cooperation platform and technical informatics framework for biobank integration between Africa and Europe. The collaboration harmonises the ethical and legal framework, biobank data representation and bioinformatiCommon Service pipelines for sharing data and knowledge among biobanks and allowing access for researchers from both continents.

Main actors from the relevant initiatives including Human Heredity and Health in Africa project (H3Africa), European Biobanking and Biomolecular Resources research infrastructure (BBMRI-ERIC) and LMIC Biobank and Cohort Network (BCNet) collaborate in B3Africa to address the following objectives:

  1. Defining an ethical and regulatory framework for biobank data sharing between Europe and Africa.
  2. Defining data models for representing biobank and research data based on existing best practices, standards and ontologies.
  3. Designing an informatics platform using existing open-source software (with eBioKit and BiBBox as essential modules) integrating workflows for biobank applications.
  4. Implementation of an education and training system for information and capacity building.
  5. Validating the B3Africa concept with existing biobanks from both continents.

B3Africa will provide the critical mass to maximise efficiency in biomedical research, supports defragmentation through integration and allows efficient leverage of existing biobanks and e-infrastructures in Europe and Africa. The technical informatics framework will be designed for easy upscaling and integration with other research infrastructures.

List of Participants

Swedish University of Agricultural Sciences; BBMRI-ERIC; Karolinska Institutet; Centre for Research Ethics and Bioethics; University of the Western Cape; Makerere University; University of Stellenbosch; IARC; International Livestock Research Institute; Medical University of Graz; Institute of Human Virology, Nigeria


 

PhenoMeNal

A comprehensive and standardized e-infrastructure
for analyzing medical metabolic phenotype data

Topic: H2020 -EINFRA-1-2014
Type of Action: RIA
Duration: 36 months
Start Date: 1 September 2015 Grant
Agreement Nr: 654241
Web: http://phenomenal-h2020.eu/home/
Coordinator: Christoph Steinbeck
Total requested Grant by Consortium: €8,810,922.00
Total requested Grant by BBMRI-ERIC: € 145,076.00
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: proposal trying to organize the metabolomics community at the European level, and we are keen to do it in full synergy with BBMRI.

Lead by European Molecular Biology Laboratory

During the next 10 years, a significant number of the 742,000,000 European citizens will have their genome determined routinely. This will be complemented with much cheaper measurement of the metabolome of biofluids which will link the genotype with data on the exposome of patients, which for the first time enables the development of a truly personalised and hand tailored medicine based on hard scientific measurement.

List of Participants:

EMBL-EBI, Imperial College of Science, Technology and Medicine, Leibniz-Instiitut für Pflanzenbiochemie, Universitat de Barcelona, University of Birmingham, Consorzio Interuniversitatio Risonanze Magnetiche di Metallo Proteine, Universiteit Leiden, The Chancellor, Masters and Scholars of the University of Oxford, Swiss Institute of Bioinformatics, Uppsala Universitet, BBMRI-ERIC, Commissariat a l’entegie atomique et aux energies alternatives, Institut national de la recherche agronomique, SRI International, The Governors of the University of Alberta/University of Alberta


 

EOSC pilot, European Open Science Cloud for Research Pilot Project, BBMRI-ERIC

EOSCpilot

The European Open Science Cloud for Research Pilot Project

Topic:  INFRADEV-04-2016
Type of Action: RIA
Duration: 24
Start date: 1st January 2017
Grant agreement: 739563
Web: https://eoscpilot.eu/
Total request Grant by Consortium: €9,953,067.50
Total request Grant by BBMRI-ERIC: €78,405.00
Linked Third Parties/BBMRI-ERIC Framework Agreement: none
Benefit/tasks for BBMRI-ERIC: Development and piloting of policies of medical data sharing as a part of European Open Science Cloud.

 

Lead by  Science  and  Technology  Facilities  Council:  The  EOSCpilot  pro- ject will support the first phase in the development of the  European  Open  Science Cloud (EOSC) as described in the EC Communication on European Cloud Initiatives [2016].

  • It will establish the governance framework for the EOSC and contribute to the devel- opment of European open science policy and best practice;
  • It will develop a number of pilots that integrate services and infrastructures to demon- strate interoperability in a number of scientific domains; and
  • It will engage with a broad range of stakeholders, crossing borders and communities, to build the trust and skills required for adoption of an open approach to scientific research.

These actions will build on and leverage already available resources and capabilities from research infrastructure and einfrastructure organisations to maximise their use across the research community. The EOSCpilot project will address some of the key reasons why European research is not yet fully tapping into the potential of data. In particular, it will:

  • reduce fragmentation between data infrastructures by working across scientific and economic domains, countries and governance models, and
  • improve interoperability between data infrastructures by demonstrating how data and resources can be shared even when they are large and complex and in varied formats.

In this way, the EOSC pilot project will improve the ability to reuse data resources and pro- vide an important step towards building a dependable open-data research environment where data from publicly funded research is always open and there are clear incentives and rewards for the sharing of data and resources.

List of Participants:

Science And Technology Facilities Council, CSC-Tieteen Tieto- tekniikan Keskus Oy, Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Ev, Eu- ropean Molecular Biology Laboratory, Surfsara BV, Stichting EGI, Centre National De La Recherche Scientifique CNRS, Karlsruher Institut Für Technologie, The University of Edin- burgh, Stichting Liber, Trust-It Services Limited, Athena Research And Innovation Center In Information Communication & Knowledge Technologies, Jisc Lbg, Partnership For Ad- vanced Computingin Europe Aisbl, Consiglio Nazionale Delle Ricerche, Istituto Nazionale di Fisica Nucleare, Stiftung Deutsches Elektronen-Synchrotron Desy, Istituto Nazionale di Geofisica e Vulcanologia, Barcelona Supercomputing Center – Centro Nacional De Su- percomputacion, Georg-August-Universitat Gottingenstiftung Offentlichen Rechts, Konink- lijke Nederlandse Akademie Van Wetenschappen – KNAW, ICOS ERIC, GEANT Vereniging, Istituto Nazionale di Astrofisica, Biobanks And Biomolecular Resources Research Infra- structure Consortium (BBMRI-ERIC), European Spallation Source ERIC, Natural Environ- ment Research Council, European X-Ray Free-Electron Laser Facility GmBH, ECRIN Eu- ropean Clinical Research Infrastructure Network, The University of Manchester United, Pin Soc.Cons. A R.L. – Servizi Didattici e Scientifici Per l’Universita di Firenze, Commis- sariat A L Energie Atomique Et Aux Energies Alternatives, Consorzio Interuniversitario Cineca


 


The website was co-funded within ADOPT BBMRI-ERIC, a project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 676550.
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